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FREQUENTLY ASKED QUESTIONS

Q:
How does pain affect the ability to sleep?
A:
Pain delays the onset of sleep, causing sleeplessness as well as frequent or early morning awakenings, preventing you from getting the deep, restful sleep you need. That’s why, even if you do get some shut-eye, you may not feel rested.

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Q:
What are the active ingredients in Advil Nighttime?
A:
Each Advil Nighttime Liqui-Gel contains 200 mg of ibuprofen and 25 mg of diphenhydramine hydrochloride, a gentle sleep enhancer. The ibuprofen relieves pain over several hours; while the diphenhydramine helps you get a full night’s sleep. The combination of these ingredients reduces your pain, shortens the time it takes to fall asleep and increases the duration of your sleep. The result: a better night's sleep.

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Q:
Why do I need a pain reliever with a sleep enhancer?
A:
If you can’t sleep because pain is keeping you up, a product that combines a pain reliever with a sleep enhancer (like Advil Nighttime) can help ease your pain and increase the duration of your sleep.

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Q:
What is the difference between Advil Nighttime and other pain relievers?
A:
Advil Nighttime is the first and only nighttime pain reliever on the Canadian market that combines the proven pain-relieving power of Advil with an added ingredient to help you sleep. Whether you have occasional muscle, back, neck or joint pain or other aches and pains, the ibuprofen in Advil Nighttime can relieve your pain over several hours. Plus, the gentle sleep enhancer works together with the ibuprofen to help you get a better night’s sleep.

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Q:
What is the safety history of the ingredients in Advil Nighttime?
A:
The two active ingredients of Advil Nighttime, ibuprofen and diphenhydramine, have a long history of safe and effective use when used as directed. The two ingredients have been used in Canada for a combined total of more than 70 years — 21 years for ibuprofen and over 50 years for diphenhydramine.

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Q:
What is the recommended dosage for Advil Nighttime?
A:
Adults and children 16-65 years: Take a single dose of 1 or 2 Liqui-Gels at night. Do not take more than the recommended dosage unless directed by a physician. Do not exceed 1200 mg of ibuprofen and 300 mg of diphenhydramine (including the 200-400 mg ibuprofen and 25-50 mg diphenhydramine hydrochloride from Advil Nighttime dose) in 24 hours. Should be taken no sooner than 4-6 hours after the last daytime ibuprofen or diphenhydramine dose. See Interactions with this Medication for examples of other products which contain these ingredients. Do not take for more than 5 consecutive nights unless directed by a physician.

Do not give to children under 16 unless directed by a physician.

Interactions with this Medication
  • Antihistamines, tranquilizers, alcohol or other sedating drugs
  • Digoxin
  • Diuretics (e.g., for bloating or heart conditions)
  • Insulin
  • Lithium
  • Medications for high blood pressure or depression, including mononamine oxidase inhibitors (MAOIs)
  • Methotrexate
  • Oral antidiabetic agents
  • Other pain relievers, sleep-aids or cold medicines

Do not take this product at the same time as other medications containing pain relievers (e.g., ibuprofen, ASA, acetaminophen, naproxen, etc.) or diphenydramine (e.g., allergy medications, sedating drugs, cough/cold/flu medications, antinausea drugs) etc.


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Q:
What are the package sizes for Advil Nighttime?
A:
Advil Nighttime is available in package sizes of 10, 20 and 40 Liqui-Gels.

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Q:
Where can I buy Advil Nighttime?
A:
You can purchase Advil Nighttime at your favourite pharmacy, in the pain reliever aisle.

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Q:
Does the product contain alcohol?
A:
No.

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Q:
Does Advil Cold & Flu contain sodium lauryl sulphate?
A:
Yes, sodium lauryl sulphate is in Advil Cold & Flu caplets.

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Q:
Where can Advil Cold & Flu be purchased?
A:
Advil Cold & Flu products are sold through a pharmacy only (self-selection area).

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Q:
Is Advil Cold & Flu safe for use during pregnancy?
A:
Advil Cold & Flu is not recommended during pregnancy unless directed by a physician.

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Q:
Advil Cold & Flu - How should Advil Cold & Flu be stored?
A:
Store at room temperature (15-30°C).

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Q:
Should I take Advil Cold & Flu that has expired?
A:
The expiry dating on the product reflects the stability of the active ingredients in Advil. We do not recommend the use of an expired product, as the potency of the product might decline past expiry.

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Q:
Advil Cold & Flu - Where can the lot number and expiry date be found on the package?
A:
Advil Cold & Flu sizes of 20 & 40: Right Side-Flap Panel.

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Q:
Is it safe to consume Advil Cold & Flu on a long-term basis?
A:
Advil Cold & Flu is not recommended for more than 3 days for fever and 5 days for pain or cold symptoms. As for long-term usage, this would be under the advice of a physician/healthcare practitioner. Do not exceed the recommended dose unless advised by a physician.

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Q:
Advil Cold & Flu - Can the product still be used if not stored according to directions i.e. frozen, refrigerated, heated, left in car, thawed, etc.?
A:
We cannot guarantee the product if it is stored beyond the recommended storage conditions. In such cases, we recommend that the product is not taken.

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Q:
Advil Cold & Flu - Does the product contain alcohol?
A:
No.

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Q:
Advil Cold & Flu - Does Advil Cold & Flu contain any animal derivatives?
A:
Yes. Stearic acid (Bovine origin).

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Q:
Does Advil Cold & Flu contain cornstarch?
A:
Yes, cornstarch can be found in Advil Cold & Flu Caplets.

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Q:
Does Advil Cold & Flu contain lactose or is the product manufactured at the same site as another lactose containing product?
A:
No.

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Q:
Is Advil Cold & Flu gluten-free and is it safe for people with celiac disease to take?
A:
Pfizer Consumer Healthcare products are gluten-free and are safe for individuals with celiac disease.

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Q:
Does Advil Cold & Flu contain nuts or is the product manufactured at the same site as another nut containing product?
A:
Pfizer Consumer Healthcare products DO NOT contain peanut oil, or any peanut or other nut derivatives and are not manufactured at the same site as another nut containing product.

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Q:
Is Advil Cold & Flu packaged in a child-resistant container?
A:

Advil Cold & Flu 20’s come with CHILD-LOK® safety cap.

Please keep in mind that child resistant does not mean child proof and all medications should be stored in a secure location.


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Q:
Does Advil Cold & Flu interact with other medications?
A:
Do not take Advil Cold & Flu if taking acetylsalicylic acid (ASA) or other products containing ibuprofen, or if allergic to ASA, salicylates or anti-inflammatory drugs, or any of its ingredients.

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Q:
What is the maximum daily dose of Advil Cold & Flu?
A:
Do not exceed 6 caplets in 24 hours, unless directed by a physician.

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Q:
Advil Cold & Flu - What happens if the product is overdosed?
A:
In case of overdose, call a poison control centre or a doctor at once even if there are no symptoms.

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Q:
Is Advil Cold & Flu safe for use during nursing/lactation?
A:
Advil Cold & Flu is not recommended during lactation unless directed by a physician.

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Q:
Is Advil gluten-free and is it safe for people with celiac disease to take?
A:
Advil is gluten-free and is safe for individuals with celiac disease.

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Q:
Does the product contain gluten or is the product manufactured at the same site as another gluten containing product?
A:
All Pfizer Consumer Healthcare products are gluten-free.

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Q:
Should I take Advil that has expired?
A:
The expiry dating on the product reflects the stability of the active ingredients in Advil. We do not recommend the use of an expired product, as the potency of the product might decline past expiry.

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Q:
Is the product in a child resistant package?
A:

Some Advil products are provided in non-childproof packaging since individuals with arthritis have difficulty opening a childproof package. Current packaging designs emphasize the CHILD-LOCK® feature of the product.

The following Advil package sizes are provided with a child-resistant cap: All sizes of Regular Strength Advil Caplets (yellow packaging).

  • Advil Extra Strength: 72's and 165's
  • Advil Muscle & Joint: 32's
  • Advil Liqui-Gels: 32's
  • Advil Extra Strength Liqui-Gels 24's

Please keep in mind that child-resistant does not mean child proof and all medications should be stored in a secure location.


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Q:
Where can the lot number and expiry date be found on the package?
A:
Right side flap of carton

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Q:
Is it safe to consume Advil on a long-term basis?
A:
Advil is recommended for duration of 5 days at a time. As for long-term usage, this would be under the advice of a physician/healthcare practitioner. Do not exceed the recommended dose unless advised by a physician.

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Q:
Can Advil still be used if not stored according to directions i.e. frozen, refrigerated, heated, left in car, thawed, etc.?
A:
We cannot guarantee the product if it is stored beyond the recommended storage conditions. In such cases, we recommend that the consumer not take the product.

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Q:
Does the product interact with other medications?
A:
Advil is not recommended for use with other nonsteroidal anti-inflammatory drugs (NSAIDs) because of the absence of any evidence demonstrating synergistic benefits and the potential for additive side effects. For more information, please consult a physician.

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Q:
Is Advil safe for use during pregnancy?
A:
Advil products are not recommended during pregnancy unless directed by a physician.

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Q:
Is Advil safe for use during nursing/lactation?
A:
The high protein binding and lower pH of breast milk versus plasma tend to inhibit the excretion of ibuprofen into breast milk. It is estimated that the infant exposure is 0.0008% of the maternal dose, which is significantly low. However, lactating mothers should consult a physician before taking Advil.

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Q:
What is the maximum daily dose of Advil?
A:
For Advil Regular Strength Tablets, Caplets, Gel Caplets, and Liqui-Gels: Do not exceed 6 tablets, caplets, gel caplets, or liqui-gels in 24 hours, unless directed by a physician. For Advil Extra Strength Caplets, Advil Muscle & Joint and Advil Extra Strength Liqui- Gels: Do not exceed 3 caplets or liqui-gels in 24 hours, unless directed by a physician.

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Q:
How should Advil be stored?
A:
Store at room temperature (15-30°C).

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Q:
Does Advil contain any animal derivatives?
A:
Yes. Advil Gel Caplets, Liqui-Gels and Extra Strength Liqui-Gels contain gelatin (bovine origin).

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Q:
Does Advil contain lactose or is the product manufactured at the same site as another lactose containing product?
A:
No.

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Q:
Does Advil contain corn starch?
A:
Yes, corn starch can be found in Advil Tablets, Caplets, Gel Caplets, and Extra Strength Caplets and Advil Muscle & Joint.

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Q:
Does Advil product contain nuts or is the product manufactured at the same site as another nut containing product?
A:
Pfizer Consumer Healthcare products DO NOT contain peanut oil, or any peanut or other nut derivatives and are not manufactured at the same site as another nut containing product.

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Q:
Does the product contain alcohol?
A:
No.

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Q:
Does Advil contain sodium lauryl sulphate?
A:
Yes, sodium lauryl sulphate is in Advil Tablets, Caplets, Advil Gel caplets, Extra Strength caplets and Advil Muscle & Joint.

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Q:
Where can Advil be purchased?
A:
Advil is sold from any retail outlet, except in Quebec. In Quebec, Advil 200 mg products are sold through a pharmacy only (self-selection area), while Advil 400 mg products are sold behind the counter through a pharmacy only.

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Q:
What happens if the product is overdosed?
A:
In case of overdose, call a poison control centre or a doctor at once even if there are no symptoms.

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Q:
Is there any latex in the product or are latex gloves used during manufacturing?
A:
Pfizer Consumer Healthcare product formulations and containers DO NOT contain latex.

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Q:
Does the product contain PPA (Phenylpropanolamine)?
A:
Since November 2001, no product on the Canadian market contains PPA, including Pfizer Consumer Healthcare Products.

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Q:
Does the product contain tartrazine?
A:
Advil Products DO NOT contain tartrazine.

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Q:
Can the product be used on pets?
A:
Ibuprofen is used for pain relief in dogs. The approximate ibuprofen dose for dogs is 5 mg/kg per day. We recommend that when used in animals, a veterinarian should be consulted. For some dogs, because it can cause gastric ulcers and performations it may not be recommended.

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Q:
Advil Cold & Sinus - How should Advil Cold & Sinus be stored?
A:
Store at room temperature (15-30°C).

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Q:
How quickly does the product work?
A:
Liqui-Gels is twice as fast as the caplets or tablets. The Liqui-Gel will start to act within 30 minutes, while the caplets might take around 50 minutes. The efficacy when it comes to pain relief will be achieved in both forms, however, when one needs a fast acting form, the Liqui-Gel is more relevant.

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Q:
Is the product safe for use in children?
A:
Children 12 and under should use Children’s Advil.

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Q:
Advil Cold & Sinus - Where can the lot number and expiry date be found on the package?
A:
Advil Cold & Sinus sizes of 10, 20 & 24: Left Side-Flap Panel. Sizes of 40, 50 & 72: Right Side-Flap Panel.

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Q:
Is Advil Cold & Sinus gluten-free and is it safe for people with celiac disease to take?
A:
Wyeth Consumer Healthcare products are gluten-free and are safe for individuals with celiac disease.

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Q:
Is it safe to consume Advil Cold & Sinus on a long-term basis?
A:
Advil Cold & Sinus is recommended for duration of 5 days at a time. As for long-term usage, this would be under the advice of a physician/healthcare practitioner. Do not exceed the recommended dose unless advised by a physician.

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Q:
Does the product contain gluten or is the product manufactured at the same site as another gluten containing product?
A:
All Wyeth Consumer Healthcare products are gluten-free.

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Q:
Should I take Advil Cold & Sinus that has expired?
A:
The expiry dating on the product reflects the stability of the active ingredients in Advil. We do not recommend the use of an expired product, as the potency of the product might decline past expiry.

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Q:
Advil Cold & Sinus - Can the product still be used if not stored according to directions i.e. frozen, refrigerated, heated, left in car, thawed, etc.?
A:
We cannot guarantee the product if it is stored beyond the recommended storage conditions. In such cases, we recommend that the product is not taken.

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Q:
Advil Cold & Sinus - Does the product contain alcohol?
A:
No.

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Q:
Is Advil Cold & Sinus packaged in a child-resistant container?
A:

Some Advil Cold & Sinus products come with CHILD-LOK® safety caps or pouches such as:

  • Advil Cold & Sinus Caplets 40's, 50's, and 72's;
  • Advil Cold & Sinus PLUS 40's, 50's, and 72's;
  • Advil Cold & Sinus Liqui-Gels 40's and 50's
Please keep in mind that child resistant does not mean child proof and all medications should be stored in a secure location.


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Q:
Advil Cold & Sinus - Does Advil Cold & Sinus contain any animal derivatives?
A:
Yes. Stearic acid (Bovine origin)

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Q:
Where can the lot number and expiry date be found on the package?
A:
Advil Pediatric Drops, Advil Pediatric Drops Fever from Colds or Flu, Children's Advil, Children’s Advil Fever from Colds or Flu, Children's Advil Cold, Children's Advil Cold & Flu Multi-symptom: Bottom Panel of packaging and on Product Label. Junior Strength Advil, Junior Strength Advil Fever from Colds or Flu: Right Panel Flap of packaging and on Product Label.

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Q:
Can the product still be used if not stored according to directions i.e. frozen, refrigerated, heated, left in car, thawed, etc.?
A:
We cannot guarantee the product if it is stored beyond the recommended storage conditions. In such cases, we recommend that the product is not taken.

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Q:
Does Advil Cold & Sinus interact with other medications?
A:
Do not take Advil Cold & Sinus if taking acetylsalicylic acid (ASA) or other products containing ibuprofen, or if allergic to ASA, salicylates or anti-inflammatory drugs, or any of its ingredients.

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Q:
Is Advil Cold & Sinus safe for use during pregnancy?
A:
Advil Cold & Sinus is not recommended during pregnancy unless directed by a physician.

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Q:
Is Advil Cold & Sinus safe for use during nursing/lactation?
A:
Advil Cold & Sinus is not recommended during lactation unless directed by a physician.

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Q:
What is the maximum daily dose of Advil Cold & Sinus?
A:
Do not exceed 6 caplets or liqui-gels in 24 hours, unless directed by a physician.

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Q:
How should Advil Cold & Sinus be stored?
A:
Store at room temperature (15-30°C).

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Q:
Does Advil Cold & Sinus contain any animal derivatives?
A:
Yes. Stearic acid (Bovine origin)

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Q:
Does Advil Cold & Sinus contain lactose or is the product manufactured at the same site as another lactose containing product?
A:
No.

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Q:
Does Advil Cold & Sinus contain cornstarch?
A:
Yes, cornstarch can be found in Advil Cold & Sinus Caplets and Advil Cold & Sinus PLUS.

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Q:
Advil Cold & Sinus - What happens if the product is overdosed?
A:
In case of overdose, call a poison control centre or a doctor at once even if there are no symptoms.

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Q:
Does Advil Cold & Sinus contain nuts or is the product manufactured at the same site as another nut containing product?
A:
Wyeth Consumer Healthcare products DO NOT contain peanut oil, or any peanut or other nut derivatives and are not manufactured at the same site as another nut containing product.

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Q:
Does Advil Cold & Sinus contain sodium lauryl sulphate?
A:
Yes, sodium lauryl sulphate is in Advil Cold & Sinus caplets.

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Q:
Where can Advil Cold & Sinus be purchased?
A:
All Advil Cold & Sinus products are sold from any retail outlet in British Columbia. In all other Provinces, Advil Cold & Sinus products are sold through a pharmacy only (self-selection area).

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Q:
Does the product contain alcohol?
A:
No.

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Q:
What happens if the product is overdosed?
A:
In case of overdose, call a poison control centre or a doctor at once even if there are no symptoms.

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Q:
How many carbohydrates are in the product?
A:
The carbohydrate content of the product is negligible.

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Q:
Is there any latex in the product or are latex gloves used during manufacturing?
A:
Wyeth Consumer Healthcare product formulations and containers DO NOT contain latex.

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Q:
Does the product contain PPA (Phenylpropanolamine)?
A:
Since November 2001, no product on the Canadian market contains PPA, including Wyeth Consumer Healthcare Products.

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Q:
Does the product contain tartrazine?
A:
Advil Cold & Sinus products DO NOT contain tartrazine.

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Q:
Is the product safe for use in children?
A:
Advil Pediatric Drops and Advil Pediatric Drops Fever from Colds or Flu can be taken by infants and children 4 months to 3 years of age. Children's Advil, Children's Advil Fever from Colds or Flu, Junior Strength Advil and Junior Strength Advil Fever from Colds or Flu can be taken by children 2-12, Children's Advil Cold & Children's Advil Cold & Flu Multi-symptom can be taken by children 6-12.

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Q:
Are the non-medicinal ingredients and dyes used in Children's Advil products safe to consume?
A:
The non-medicinal ingredients, including dyes, present in Children's Advil products are safe and allowed for use under the current Canadian Food & Drug Regulations. For those parents who prefer a product without dye, Children's Advil has a dye free pediatric drop, dye free suspension and dye free chewable.

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Q:
Children's Advil - Does the product contain alcohol?
A:
No.

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Q:
Does Children's Advil contain gluten or is the product manufactured at the same site as another gluten containing product?
A:
Children's Advil is gluten-free.

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Q:
Should I give Children's Advil to my child after the expiry date?
A:
The expiry dating on the product reflects the stability of the active ingredients in Children's Advil. We do not recommend continued use of an expired product as the potency might decline past expiry date.

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Q:
Is Children's Advil packaged in child-resistant containers?
A:
All Children's Advil products come with Child-Lok® safety caps. Please keep in mind that child-resistant does not mean child proof and all medications should be stored in a secure location.

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Q:
Where can the lot number and expiry date be found on the package?
A:
Children's Advil Cold, Children's Advil Suspension, & Advil Pediatric Drops: bottom panel of packaging and on product label. Junior Strength Advil: right panel flap of packaging and on product label.

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Q:
Is it safe to consume Children's Advil on a long-term basis?
A:
Children's Advil is recommended for 5 days for pain relief and 3 days for fever relief. Consult a physician if the symptoms persist for more than 3 days. Do not exceed the recommended dose unless advised by a physician.

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Q:
Can Children's Advil still be used if not stored according to directions?
A:
We cannot guarantee the product if it is stored beyond the recommended storage conditions. In such cases, we recommend that the product is not taken.

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Q:
Does Children's Advil interact with other medications?
A:
Do not administer to children taking acetylsalicylic acid (ASA) or other products containing ibuprofen, or to anyone who has had an allergic reaction (difficulty in breathing, swelling, hives or shock) after using ASA, other salicylates or anti-inflammatory drugs. For more information consult the consumer information provided with the product or consult a physician before use.

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Q:
What is the maximum daily dose of Children's Advil?
A:
For Advil Pediatric Drops, Advil Pediatric Drops Fever from Colds or Flu, Children's Advil, Children's Advil Fever from Colds or Flu: 3 doses a day (dose dependent on age/weight), or as directed by a doctor. For Junior Strength Advil, Junior Strength Advil Fever from Colds or Flu, Children's Advil Cold & Children's Advil Cold & Flu Multi-symptom: 4 doses a day (dose dependent on age/weight), or as directed by a doctor.

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Q:
How should Children's Advil be stored?
A:
Advil Pediatric Drops, Advil Pediatric Drops Fever from Colds or Flu, Children's Advil Suspension, Children's Advil Fever from Colds or Flu, Children's Advil Cold, Children's Advil Cold & Flu Multi-symptom: Store at room temperature (15-30°C). Junior Strength Advil, Junior Strength Advil Fever from Colds or Flu: Store at room temperature (20°-25°C), protect from moisture and excessive heat.

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Q:
Should I use Children's Advil for my child's fever?
A:
Yes. Children's Advil has been scientifically proven to be effective in the reduction of fever in children when used and dosed as per directions on the product label.

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Q:
Children's Advil - What should the patient do in case of accidental overdose?
A:
In case of overdose, call a poison control centre, or a doctor at once even if there are no symptoms.

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Q:
Does Children’s Advil contain any animal derivatives?
A:
Yes. Junior Strength Advil, Junior Strength Advil Fever from Colds or Flu: Gelatin (porcine origin). There are no animal derivatives in Advil Pediatric Drops, Advil Pediatric Drops Fever from Colds or Flu, Children's Advil, Children's Advil Fever from Colds or Flu, Children's Advil Cold, Children's Advil Cold & Flu Multi-symptom.

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Q:
Does Children's Advil contain lactose or is the product manufactured at the same site as another lactose containing product?
A:
No.

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Q:
Does Children's Advil contain corn starch?
A:
No.

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Q:
Does Children's Advil contain nuts or is the product manufactured at the same site as another nut containing product?
A:
Pfizer Consumer Healthcare products DO NOT contain peanut oil, or any peanut or other nut derivatives and are not manufactured at the same site as another nut containing product.

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Q:
Does Children's Advil contain sodium lauryl sulphate?
A:
No.

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Q:
Does the product contain alcohol?
A:
No.

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Q:
Where can Children's Advil be purchased?
A:
All Children's Advil (except Children's Advil Cold & Children's Advil Cold & Flu Multi-symptom) products are sold from any retail outlet, except in Quebec. In Quebec, these products are sold through a pharmacy only (self-selection area). Children's Advil Cold & Children's Advil Cold & Flu Multi-symptom are sold from any retail outlet in British Columbia and Alberta. In all other Provinces, Children's Advil Cold & Children's Advil Cold & Flu Multi-symptom are sold through a pharmacy only (self-selection area).

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Q:
What should the patient do in case of accidental overdose?
A:
In case of overdose, call a poison control centre, or a doctor at once even if there are no symptoms.

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Q:
Is there any latex in the product or are latex gloves used during manufacturing?
A:
Wyeth Consumer Healthcare product formulations and containers DO NOT contain latex.

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Q:
Why is Children's Advil Pediatric Drops still available?
A:
Children's Advil Pediatric Drops does not contain any cough or cold ingredients and may continue to be used in accordance with the label directions.

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Q:
Does the product contain PPA (Phenylpropanolamine)?
A:
Since November 2001, no product on the Canadian market contains PPA, including Wyeth Consumer Healthcare Products.

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Q:
Does the product contain tartrazine?
A:
Children’s Advil products DO NOT contain tartrazine.

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Liqui-Gels® is a trademark or registered trademark of Catalent Pharma Solutions.
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